Aging May Tinker With Thirst [brain]

Aging May Tinker With Thirst

With Age, Thirst Nerves May Not Work as Well, Paving the Way for Dehydration

Medically Reviewed by Louise Chang, MD on December 17, 2007

Dec. 17, 2007 -- Scientists have a new clue about why the elderly may be vulnerable to dehydration.

Age-related changes in certain nerves in the mouth, throat, and stomach may be the problem.

A new study shows that healthy men in their 20s or 60s get equally thirsty when injected with salt water. But older men drank half as much water as younger men to slake their thirst.

The men got brain scans using positron emission tomography (PET) during the experiment. Those brain scans showed different patterns of activity in brain areas related to thirst.

While the men drank water to soothe their thirst, the PET scans showed less activity in a certain brain area in the older men than in the younger men.

That may mean that the nerves that carry the "I'm thirsty!" signal from the mouth, throat, and stomach don't work as well with age.

It may be a good idea to schedule drinking to reduce the chances of elderly dehydration, note the researchers. They included Gary Egan, PhD, of the Howard Florey Institute at Australia's University of Melbourne.

Their findings appear in this week's early online edition of Proceedings of the National Academy of Sciences.

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